Speaker: Juan Antonio Gordillo Gayo.
Abstract: Proteins are the main executors of life: they catalyze reactions, transmit signals, structure tissues, and regulate essential cellular processes. Their function is intimately determined by the sequence of amino acids that compose them, which is why modern biology has long sought to understand how these sequences encode structure and function.
In this talk, we aim to introduce, in an accessible way, the key biological concepts relevant to the use of Protein Language Models (PLMs). We will review the main formats and types of data used to represent proteins, explore essential tools for obtaining and processing such data, and present the most representative state-of-the-art PLMs—focusing on the type of information they rely on and how it can be used for specific prediction and analysis tasks in computational biology.